THE STETHO

Super Refractory Status Epilepticus Secondary to Salmonellosis: A Case Report

Syed Osama Husain — 2025-09-21

The term super-refractory status epilepticus (SRSE) refers to status epilepticus (SE) that lasts for 24 hours or longer after the administration of anesthetic agents, including situations in which the status epilepticus recurs after the anesthetic agent is reduced or removed. Status epilepticus is most frequently brought on by acute brain damage or insult. It can also occur as a primary idiopathic disorder in patients without an established epilepsy diagnosis and refer to as new-onset refractory status epilepticus (NORSE). The etiology of SRSE is multifaceted, and the majority of the time, after rigorous investigations, the root cause is discovered within 24-72 hours. The etiology can be attributed to autoimmune, paraneoplastic, and infectious origins in more than 50% of cases. In the example presented here, non-typhoidal salmonellosis led to the development of SRSE in a 22-year-old female patient, and the infection was resistant to a variety of broad-spectrum antibiotics. The patient was given numerous anti-epileptic medications (AED), anesthetic drugs, and then culture-specific antibiotics. These treatments eventually stopped the seizures, which momentarily resulted in great clinical improvement.

Urology Unlocked

Praveen Subbiah — 2025-09-10

Urology Unlocked by Dr. Praveen Subbiah offers a clear and accessible guide to the essentials of urology. Designed for students, residents, and healthcare professionals, the book breaks down complex concepts into practical knowledge that can be easily applied in clinical settings. Covering anatomy, common urologic conditions, diagnostic tools, and treatment approaches, it serves as both an introduction and a quick reference. Dr. Subbiah’s structured explanations, case-based insights, and focus on fundamentals make this book a reliable resource for unlocking the core principles of urology.

Principles of Medicine: From Classroom to Clinic

Urooba Karim — 2025-09-10

Principles of Medicine: From Classroom to Clinic bridges the gap between medical theory and real-world practice. Written for medical students, residents, and early-career clinicians, this book translates classroom learning into practical clinical skills. It covers core medical concepts, diagnostic reasoning, patient care approaches, and case-based examples that prepare readers for the transition into clinical environments. With clear explanations and a structured format, it serves as both a study aid and a practical reference for everyday clinical decision-making.

Pain and Diabetes: An Interdisciplinary Approach

Zarshal Zakir — 2025-08-25